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The Global Infrastructure for Precision Medicine

WuXi NextCODE enables organizations worldwide to use the full power of the genome to improve health and support wellness. We do that by providing the most powerful technology platform for using sequence data – at scale, real-time, online – as well as all the capabilities and know-how required to generate and deploy the data you need to identify the key variants in the genome that underlie your patients’ phenotype.

Our Platform


Organize

Genomics is a big data challenge with a difference. The foundation of the WuXi NextCODE advantage is the only data architecture optimized specifically for massive genomic data. It was built to manage and mine the largest collection of whole-genome sequence data and is the only system proven with data at population scale.

Underpinning the world’s preeminent precision medicine enterprises, it’s your operating system for the human genome – giving you on-the-fly queries and joins between all your sequences and all standard global reference sets; optimized for cluster computing; with unmatched computational and cost efficiency.

With integrated query languages for genomic and phenotypic data, and the ability to run and integrate with Python, R and other common informatics tools and languages, we enable the seamless ad hoc interrogation of phenotype and sequence data to deliver precision care.

Mine

Leveraging the structure of the genome itself, our proprietary tools give you an unmatched search engine for asking the questions you want and getting the answers you need. Our interfaces seamlessly tap into all your data – including global reference data – to solve cases and identify key variants whatever your challenge:
Clinical Diagnostics: Our Clinical Sequence Analyzer interpretation and reporting system leverages an unmatched, constantly updated knowledgebase as well as leading-edge mode of inheritance and de novo detection.
Clinical Applications: Battle-tested at unrivalled scale, our Sequence Miner enables you to identify key variants linked to patient phenotype using all of your sequence and phenotypic data, using incorporating your own scripts and tools as you wish.
Cancer: Our Tumor Mutation Analyzer enables you to compare tumor and normal whole genome data backed with always-on reference to identify mutations driving individual tumors.
Deep Learning: We are pioneering the use of artificial intelligence in the life sciences. Our proprietary DeepCODE algorithms use DNA, RNA, microarray and protein data to map pathways and identify signatures that can instantly and automatically classify disease and identify novel genomic variants to power improved healthcare through new diagnostic tests and detailed understanding of biological pathways.

Share

The efficiency of GOR has enabled us to provide the global genomics community with the first functioning internet of DNA.

The ability to use full-resolution genomic data over an ordinary internet connection, through integrated clinical and sequence analysis interfaces, is unique and intrinsic to WuXi NextCODE. You can fully use all of your data wherever it resides – whether on your desktop server, elsewhere in your building, in the cloud or on the other side of the planet. That means that you can collaborate using your own and partners’ patient data, analyze clinical data residing on servers on different continents and access global reference sets all as though they were on your server.

Our platform enables you to interact with the largest community of genomes in the world, with full access control to your own data. We call this community the WuXi NextCODE Exchange, and it is already providing global access to the world’s largest autism dataset providing the foundation for global data sharing.

Our Capabilities

Along with uniquely powerful means of using your genomic data, WuXi NextCODE offers deep expertise and end-to-end solutions for generating and deploying it. These include clinical diagnostics and applications; a full range of CAP- and CLIA-certified sequencing; secondary analysis; cloud solutions from leading global providers and the option for HIPAA-compliant storage. We are here to help with whatever piece of the puzzle you are missing or with bundled or completely integrated solutions, customized to meet your needs.


Patient Collections

Because our platform underpins large-scale projects around the world, we can help you manage large collections of patients. We have experience with consents, sample collection, molecular profiling and medical data management.

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Sequencing

Our high-throughput, CAP- and CLIA-certified facilities offer best-in-class quality. From single clinical samples to population-scale projects, we can meet any need. Run WGS, RNAseq and more with confidence and compliance.

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Cloud

Choose to run our system in the cloud and get elastic scalability, compliance and best-in-class security. Join patient collections and leverage full-resolution data without moving big files. Build a knowledge base within your institution or with collaborators around the world.

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Clinical Applications

Genomic big data is the key to revolutionizing healthcare. Find the key variants linked to patient phenotypes and responder status, and use these insights to power better patient care.

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Processing

It doesn’t get any more flexible than this. You can use your own pipeline, choose from a large number of other proven options, validated across multiple projects.

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Clinical Interpretation

Shorten workflows and solve more cases. Solve rare disease cases within minutes, conduct tumor/germline analyses to identify cancer-related variants and generate well-patient reports with risk assessments and carrier status.

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